Dott.ssa Imma Iovinella

Sede di Firenze

Curriculum Vitae




Personal information :
Immacolata Iovinella Telephone : +39 3333921995 Email: imma.iovinella@gmail.com Date of birth : 17 Agosto 1984


Work address :
Dipartimento di Biologia Università degli Studi di Firenze Via Madonna del Piano 6, 50019 Sesto Fiorentino (FI)

Current occupation :
Chief Executive Officer Osmes s.r.l.
Post–doc fellowship at Dipartimento di Biologia, University of Florence.
Career/Education :

May 2016– April 2017 Post–doc fellowship "Dott. Giuseppe Guelfi" established by Accademia dei Lincei. Aim of the research: ‘Olfactory proteins of the parasite mite (Varroa destructor) of Apis mellifera‘. Supervisor: Dr. Francesca Romana Dani.

November 2015– April 2016 Post–doc fellowship at Dipartimento di Biologia, University of Florence in "Study of cuticular hydrocarbons of Bombus terrestris larvae". Supervisor: Dr. Francesca Romana Dani. 29

June–3 July 2015 7th Summer School in "Computational Mass Spectrometry–Based Proteomics" at Max Planck Institute of Biochemistry (Martinsried, Germany)

August 2014–June 2015 Post–doc in "gnomic and proteomic analysis of afro–tropical malaria vector Anopheles gambiae" at department of Public Health and Infectious Diseases, University "La Sapienza", Rome. Supervisor: Prof. Alessandra della Torre.

September 2013–April 2014 Post–doctoral visiting scholarship at the Institute of Zoology (Group of Insect Behavioral Physiology and Biochemistry), Chinese Academy of Sciences, Datum Road, Beijing 100101,China Lab. of Prof. Wang Chen–Zhu

August 2009–July 2013 Grant position from European project "ENAROMaTIC" (European Network for Advanced Research on Olfaction for Malaria Transmitting Insect Control). Aim of the research: Expression and functional characterization of Odorant–binding proteins in Anopheles gambiae.

January 2010– December 2012 PhD student in "Molecular Biotechnology", PhD School BIOS (Biological and Molecular Sciences), University of Pisa, Lungarno Pacinotti, 43/44 PISA Thesis Title: "Semiochemicals and olfactory proteins in mosquito control" Research topic: biochemical study of the olfactory system in mosquitoes in order to devise strategies alternative to insecticides for population control, with the main objective of discovering and design new mosquito repellents. Supervisor: Prof. Paolo Pelosi Laboratory: Department of Agricolture, Food and Environment, University of Pisa, Via del Borghetto 80, 56124, Pisa (Italy)

December 2008 MSc in "Biomolecular science and tecnologies" at University of Pisa. Marks: 110/110 cum laude. Experimental Thesis title: "Expression and characterization of CSPs (Chemosensory proteins) in Apis mellifera " Department of Agriculture, Food and Environment, University of Pisa Via del Borghetto, 80, 56124 Pisa, Italy Supervisor : Prof. Paolo Pelosi

June 2008 lab–experience in the section of "Insect molecular biology" of Rothamsted Research, Harpenden, UK, Lab. of Jing–Jiang Zhou.

October 2006 BSc in "Molecular biological sciences" at University of Pisa. Marks: 110/110 cum laude Experimental thesis title: "Studio di inibizione dell‘enzima Leucil Aminopeptidasi purificato dal cristallino bovino" Department of Biology, University of Pisa Via San Zeno, 31 I–56123 Pisa, Italy. Supervisor: Dr. Mario Cappiello

2003–2008 Student in Molecular Biology at University of Pisa, Italy.

2003 High school diploma in Science

Languages : Mother tongue: Italian Other language: English, good spoken and written
Technical skills and competences :

Cloning; site–directed mutagenesis; expression of recombinant protein in bacteria and yeasts; PCR; electrophoresis of proteins and nucleic acids; purification of proteins (chromatographic separation); ligand binding assays; Western blotting; behaviour studies to evaluate efficacy of mosquito repellents; data analysis of proteomic data


Computer skills and competences :

Good command of Microsoft Office tools (Word , Excel and PowerPoint ) Operating Systems Windows 2000, XP, Vista, 7 Software: ChemSketch (and other program to make chemical structure); MaxQuant and Perseus for proteomic data. FigTree v.1.3.1 SwissPdb Viewer programme "Deep–View" Web molecular tools: BLAST; ClustalW2; server for prediction of signal peptide; restriction mapping DNA sequencing; ExPASy (ProtParam tool; Translate tool); Swiss model

Publications :

International peer–reviewed journals

Citations: 298

H–index: 8

1. Iovinella I., Caputo B., della Torre A., Dani F.R. (2016) "Wide–scale analysis of protein expression in head and thorax of Aedes albopictus females" Journal of insect Physiology submitted
2. Zhu J., Iovinella I. (*), Dani F.R., Liu Y–L, Huang L–Q, Liu Y., Wang C–Z, Pelosi P., Wang G. (2016) "Conserved chemosensory proteins in the proboscis and eyes of Lepidoptera" International Journal of Biological Sciences, 12(11):1394–1404. doi:10.7150/ijbs.16517. IF: 3.982

3. Iovinella I., Ban L., Song L., Pelosi P, Dani F.R. (2016) "Proteomic analysis of castor bean tick Ixodes ricinus: A focus on chemosensory organs" Insect Biochemistry and Molecular Biology 78, 58–68. IF: 3.767

4. Iovinella I., Caputo B., Michelucci E., Dani F.R., della Torre A. (2015) "Candidate biomarkers for mosquito age–grading identified by label–free quantitative analysis of protein expression in Aedes albopictus females." Journal of Proteomics 128:272–279. IF: 3.867

5. Guarna M. M., Melathopoulos A. P., Huxter E., Iovinella I., Parker R., Stoynov N., Tam A., Moon K–M, Chan Q. W. T., Pelosi P., White R., Pernal S. F., Foster L. J. (2015) "A Search for Protein Biomarkers Links Olfactory Signal Transduction to Social Immunity" BMC Genomics 16:63 DOI 10.1186/s12864–014–1193–6. IF: 3.867

6. Pelosi P., Iovinella I., Felicioli A., Dani F.R. (2014) "Soluble proteins of chemical communication: an overview across arthropods" Frontiers in Physiology 5: 320. IF: 4.031

7. Pelosi P., Mastrogiacomo R., Iovinella I., Tuccori E., Persaud K.C. (2014) "Structure and biotechnological applications of odorant– binding proteins." Applied microbiology and biotechnology 98 (1), 61–70. IF: 3.376

8. Mastrogiacomo R., Iovinella I. (*), Napolitano E. (2014) "New fluorescent probes for ligand–binding assays" Biochemical and biophysical research communications 446 (1), 137–142. IF: 2.371

9. Iovinella I., Pelosi P., Conti B. (2013) "A rationale to design longer lasting mosquito repellents" Parasitology research 113 (5), 1813–1820. IF: 2.027

10. Mastrobuoni G., Qiao H., Iovinella I., Niccolini A., Caputo B., della Torre A., Kempa S., Felicioli A., Pelosi P.,Moneti G., Dani F.R.(2013) "A proteomic investigation of olfactory proteins in Anopheles gambiae" PloS one 8 (11), e75162. IF: 3.54

11. Ban L., Napolitano E., Serra A., Zhou X., Iovinella I., Pelosi P. (2013) "Identification of pheromone–like compounds in male reproductive organs of the oriental locust Locusta migratoria" Biochemical and biophysical research communications 437 (4), 620–624. IF: 2.371

12. Iovinella I., Bozza F., Caputo B., Della Torre A., Pelosi P. (2013) "Ligand binding study of Anopheles gambiae Chemosensory proteins" Chemical senses 38 (5), 409–419. IF: 2.93

13. Yin X–W., Iovinella I. (*), Marangoni R., Cattonaro F., Flamini G., Sagona S., Zhang L., Pelosi P., Felicioli A. (2013) "Odorant–binding proteins and olfactory coding in the solitary bee Osmia Cornuta" Cellular and Molecular Life Sciences 70 (16), 3029–3039. IF: 5.694


14. Zhou X.H., Ban L.P., Iovinella I., Zhao L.J., Gao Q., Felicioli A., Sagona S., Pieraccini G., Pelosi P., Zhang L., Dani F.R. (2012) "Diversity, abundance and sex–specific expression of chemosensory proteins in the reproductive organs of the locust Locusta migratoria manilensis" Biological chemistry 394 (1), 43–54 . IF: 4.41

15. Sun Y.F., De Biasio F., Qiao H.L., Iovinella I., Yang S.X., Ling Y., Riviello L., Battaglia D., Falabella P., Yang X.L., Pelosi P. (2012) "Two odorant–binding proteins mediate the behavioural response of aphids to the alarm pheromone (E)–– farnesene and structural analogues" PloS one 7 (3), e32759. IF: 3.54

16. Spinelli S., Lagarde A., Iovinella I., Legrand P., Tegoni M., Pelosi P., Cambillau C. (2012) "Crystal structure of Apis mellifera OBP14, a C–minus odorant–binding protein, and its complexes with odorant molecules" Insect biochemistry and molecular biology 42 (1), 41–50. IF: 3.767

17. Iovinella I., Dani F.R., Niccolini A., Sagona S., Michelucci E., Gazzano A., Turillazzi S., Felicioli A., Pelosi P. (2011) "Differential Expression of Odorant–Binding Proteins in the mandibular glands of the Honey Bee According to caste and age" Journal of proteome research 10 (8), 3439–3449. IF: 4.173

18. Dani F.R., Iovinella I. (*), Felicioli A., Niccolini A., Calvello M.A., Carucci M.G., Qiao H., Pieraccini G., Turillazzi S., Moneti G., Pelosi P. (2010) "Mapping the expression of soluble olfactory proteins in the honeybee" Journal of proteome research 9 (4), 1822–1833. IF: 4.173

(*) co–first author
Conference communications:

Oral presentation: "Odorant–binding proteins and Chemosensory proteins of the honeybee: a proteomic approach" Iovinella I., Calvello M.A., Carucci M.G., Qiao H., Niccolini A., Felicioli A., Dani F.R., Turillazzi S., Pelosi P. 11th ESITO (European Symposium for Insect Taste and Olfaction); September 19–24 2009, Villasimius, Cagliari, Italy Poster: "The Odorant–binding Proteins of Anopheles gambiae" Iovinella I., Dani F.R., Mastrobuoni G., Boscaro F., Qiao H., Sagona S., Caputo B., Felicioli A., Della Torre A., Pelosi P. ECRO (European chemoreception research organization) XXI Congress; Settembre 7–10 2011, Manchester, UK

Abstract: "Protein biomarkers link olfactory signal transduction to social immunity in honey bees" M. Marta Guarna, Kyung–Mee Awards Moon, Immacolata Iovinella, Mathew Bundala, Andony P Melathopoulos, Elizabeth Huxter, Robert Parker, Nikolay Stoynov, Queenie WT Chan, Paolo Pelosi, Rick White, Stephen F Pernal, and Leonard J Foster HUPO (Human Proteome Organization) 2015; Settembre 27–30 2015; Vancouver, British Columbia, Canada.

Abstract: "Soluble Olfactory Proteins. Is there anything especial in Social Hymenoptera?" Dani, F.R., Iovinella I., Turillazzi S., Felicioli, A., Pelosi P. 17· Congresso IUSSI (International Union for the Study of Social Insects), Cairns, Queensland, Australia.
Abstract: "A proteomic–based "shotgun" approach opens new perspectives to mosquito age–grading" I. Iovinella, B. Caputo, E. Michelucci, F. Dani, A. della Torre. ASTMH (American Society of Tropical Medicine and Hygiene) 64th Annual Meeting October 25–29, 2015 Philadelphia Marriott Downtown Philadelphia, Pennsylvania USA.

Poster: "Social grooming in the honeybee Apis mellifera: efficiency, spatio–temporal occurrence and physiological correlates" A. Cini, A. Bordoni, F. Cappa, I. Petrocelli, I. Iovinella, F. R. Dani, S. Turillazzi, R. Cervo. EuroIUSSI (International Union for the Study of Social Insects) August 8–11, 2016 Helsinki, Finland

Awards:
Best poster presentation, Annual meeting of the PhD School BIOS, University